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Article

Multiple proliferation-survival signalling pathways are simultaneously active in BRAF V600E mutated thyroid carcinomas.

Experimental and molecular pathology - 1 Dec 2015

Rahman Md Atiqur, Salajegheh Ali, Smith Robert Anthony, Lam Alfred King-yin

Abstract excerpt

BACKGROUND AND OBJECTIVES: BRAF is an oncogene which involves in pathogenesis of many thyroid carcinomas.The aim of our study was to investigate whether the downstream signalling pathway of BRAF and AKT kinase signalling pathways were active in BRAF V600E mutated thyroid carcinoma cells. METHODS: Five thyroid (papillary and undifferentiated) carcinoma cell lines and one non-cancer thyroid cell line were screened...

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to MAP Kinase Signaling System

Share to Oncogene Protein v-akt

Share to Proto-Oncogene Proteins B-raf

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Source

Identifiers

PMID: 26403329
DOI: 10.1016/j.yexmp.2015.09.006

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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