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Article

Lack of association between BRAF V600E mutation and mitogen-activated protein kinase activation in papillary thyroid carcinoma.

Pathology international - 1 Jan 2007

Zuo Hui, Nakamura Yasushi, Yasuoka Hironao, Zhang Ping, Nakamura Misa, Mori Ichiro, Miyauchi Akira, Kakudo Kennichi

Abstract excerpt

The BRAF V600E mutation has been identified in a high proportion of papillary thyroid carcinoma (PTC). In cell lines and a transgenic mouse model it has been demonstrated that the mutation constitutively activates the mitogen-activated protein kinase (MAPK) pathway but in human PTC samples its ef...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17199737
DOI: 10.1111/j.1440-1827.2007.02050.x

Genes

BRAF
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17199737-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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