Article
Polarization and reprogramming of myeloid-derived suppressor cells.
Journal of molecular cell biology - 1 Jun 2013
Yang Wen-Chin, Ma Ge, Chen Shu-Hsia, Pan Ping-Ying
Abstract excerpt
Myeloid-derived suppressor cells (MDSC) have recently emerged as one of the central regulators of the immune system. In recent years, interest in understanding MDSC biology and applying MDSC for therapeutic purpose has exploded exponentially. Despite recent progress in MDSC biology, the mechanisms underlying MDSC development from expansion and activation to polarization in different diseases remain poorly...
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