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Myeloid-Derived Suppressor Cells in Solid Tumors

17 Jan 2022

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) are one of the main suppressive cell population of the immune system. They play a pivotal role in the establishment of the tumor microenvironment (TME). In the context of cancers or other pathological conditions, MDSCs can differentiate, expand, and migrate in large quantities during circulation, inhibiting the cytotoxic functions of T cells and NK cells. This process is...

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PMID: 35053426
DOI: 10.3390/cells11020310

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