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Article

Phenotypic plasticity of MDSC in cancers.

Immunological investigations - 1 Jan 2012

Manjili Masoud H

Abstract excerpt

Myeloid-derived suppressor cells (MDSCs) were initially reported as suppressor of the adaptive immune responses against cancer and other diseases. However, emerging evidence suggest that MDSCs may also support anti-tumor immune responses under certain conditions or may inhibit tumor growth. In the present mini-review, we suggest that such opposing functions of MDSCs are due to phenotypic plasticity of the myeloid...

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Identifiers

PMID: 23017142
DOI: 10.3109/08820139.2012.673670

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