Article
Myeloid-Derived Suppressor Cells.
Cancer immunology research - 1 Jan 2017
Gabrilovich Dmitry I
Abstract excerpt
Myeloid cells developed evolutionarily as a major mechanism to protect the host. They evolved as a critical barrier against infections and are important contributors to tissue remodeling. However, in cancer, myeloid cells are largely converted to serve a new master-tumor cells. This process is epitomized by myeloid-derived suppressor cells (MDSC). These cells are closely related to neutrophils and monocytes....
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