Article
Insights into Myeloid-Derived Suppressor Cells in Inflammatory Diseases.
Archivum immunologiae et therapiae experimentalis - 1 Aug 2015
Kwak Yewon, Kim Hye-Eun, Park Sung Gyoo
Abstract excerpt
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells involved in immune regulation. This population subdivides into granulocytic MDSCs and monocytic MDSCs, which regulate immune responses via the production of various molecules including reactive oxygen species, nitric oxide, arginase-1, interleukin-10, and transforming growth factor-β. Most studies of MDSCs focused on their role in...
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