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Article

Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue.

Genome biology - 25 Mar 2013

Mayrhofer Markus, DiLorenzo Sebastian, Isaksson Anders

Abstract excerpt

Whole-genome sequencing of tumor tissue has the potential to provide comprehensive characterization of genomic alterations in tumor samples. We present Patchwork, a new bioinformatic tool for allele-specific copy number analysis using whole-genome sequencing data. Patchwork can be used to determine the copy number of homologous sequences throughout the genome, even in aneuploid samples with moderate sequence...

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Identifiers

PMID: 23531354
DOI: 10.1186/gb-2013-14-3-r24
PMCID: PMC4053982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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