Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing.

Nucleic acids research - 19 Sept 2016

Shen Ronglai, Seshan Venkatraman E

Abstract excerpt

Allele-specific copy number analysis (ASCN) from next generation sequencing (NGS) data can greatly extend the utility of NGS beyond the identification of mutations to precisely annotate the genome for the detection of homozygous/heterozygous deletions, copy-neutral loss-of-heterozygosity (LOH), allele-specific gains/amplifications. In addition, as targeted gene panels are increasingly used in clinical sequencing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma of Lung
Share to Clone Cells
Share to Databases, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Gene Dosage

Share to Genetic Heterogeneity

Share to Loss of Heterozygosity

Source

Open in PubMed Open full text

Identifiers

PMID: 27270079
DOI: 10.1093/nar/gkw520
PMCID: PMC5027494

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FACETS: allele-specific copy number and clonal heterogeneity analysis tool for high-throughput DNA sequencing.PMID 27270079Read ↗

FACETS: Fraction and Allele-Specific Copy Number Estimates from Tumor Sequencing.Semantic proximity Read ↗

CANCAN: high-resolution copy number and mutation heterogeneity analysis of DNA sequence data for clinical applicationsSemantic proximity Read ↗

Reliable analysis of clinical tumor-only whole exome sequencing dataSemantic proximity Read ↗

CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications.Semantic proximity Read ↗

Reliable Analysis of Clinical Tumor-Only Whole-Exome Sequencing Data.Semantic proximity Read ↗

Alleloscope: Integrative single cell analysis of allele-specific copy number alterations and chromatin accessibility in cancerSemantic proximity Read ↗

OncoSNP-SEQ: a statistical approach for the identification of somatic copy number alterations from next-generation sequencing of cancer genomes.Semantic proximity Read ↗

Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue.Semantic proximity Read ↗

Alleloscope: Integrative single cell analysis of allele-specific copy number alterations and chromatin accessibility in cancerSemantic proximity Read ↗

Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity.Semantic proximity Read ↗

CNA Explorer and anaLyzer (CNAEL): an interactive web application and standard operating procedure enabling efficient clinical review and reporting of complex NGS-derived tumor copy number profilesSemantic proximity Read ↗

ClinCNV: novel method for allele-specific somatic copy-number alterations detectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.