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Article

FACETS: Fraction and Allele-Specific Copy Number Estimates from Tumor Sequencing.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Arora Arshi, Shen Ronglai, Seshan Venkatraman E

Abstract excerpt

Clinical sequencing studies routinely involve molecular profiling of patients for mutations and copy number alterations. However, detection of "actionable" aberrations to guide treatment decisions require accurate, tumor purity-, ploidy-, and clonal heterogeneity-adjusted integer copy number calls. In this chapter, we describe the FACETS algorithm, an Allele-Specific Copy Number (ASCN) analysis tool with a broad...

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PMID: 35751811
DOI: 10.1007/978-1-0716-2293-3_7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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