Article
Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis.
Development (Cambridge, England) - 1 May 2013
Koltowska Katarzyna, Apitz Holger, Stamataki Despina, Hirst Elizabeth M A, Verkade Heather, Salecker Iris, Ober Elke A
Abstract excerpt
Tightly controlled DNA replication and RNA transcription are essential for differentiation and tissue growth in multicellular organisms. Histone chaperones, including the FACT (facilitates chromatin transcription) complex, are central for these processes and act by mediating DNA access through nucleosome reorganisation. However, their roles in vertebrate organogenesis are poorly understood. Here, we report the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
