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Article

Paf1 complex homologues are required for Notch-regulated transcription during somite segmentation.

EMBO reports - 1 Sept 2007

Akanuma Takashi, Koshida Sumito, Kawamura Akinori, Kishimoto Yasuyuki, Takada Shinji

Abstract excerpt

Members of the yeast polymerase-associated factor 1 (Paf1) complex, which is composed of at least five components (Paf1, Rtf1, Cdc73, Leo1 and Ctr9), are conserved from yeast to humans. Although these proteins have been implicated in RNA polymerase II-mediated transcription, their roles in vertebrate development have not been explained. Here, we show that a zebrafish mutant with a somite segmentation defect is...

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Identifiers

PMID: 17721442
DOI: 10.1038/sj.embor.7401045
PMCID: PMC1973952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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