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Article

Genomic heterogeneity contributed to different prognosis between adult and pediatric acute lymphoblastic.

Journal of leukocyte biology - 1 Sept 2022

Chen Yanxin, Zheng Yongzhi, Hong Yunda, Wen Jingjing, Li Jiazheng, Huang Yan, Chen Yi, Zheng Xiaoyun, Yang Ting, Xu Yangqi, Zheng Jing, Hu Jianda

Abstract excerpt

The prognosis of acute lymphoblastic leukemia (ALL) in adults is inferior to that in children. Hence, ALL remains challenging to cure in the adult population. Aberrant genetic alterations have been observed in ALL, although the patterns of differential gene alterations in adult and pediatric ALL have not been comprehensively determined on a genome-wide scale. We investigated the biologic differences in genomic...

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PMID: 35172382
DOI: 10.1002/JLB.5A0721-361R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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