ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A MIGICCL Study.

doi:10.1016/j.arcmed.2016.12.003

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ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A MIGICCL Study.

Archives of medical research - 1 Nov 2016

Bekker-Méndez Vilma Carolina, Núñez-Enríquez Juan Carlos, Torres Escalante José Luis, Alvarez-Olmos Enrique, González-Montalvoc Pablo Miguel, Jiménez-Hernández Elva, Sansón Aurora Medina, Leal Yelda A, Ramos-Cervantes María Teresa, Guerra-Castillo Francisco Xavier, Ortiz-Maganda Mónica Patricia, Flores-Lujano Janet, Pérez-Saldivar Maria Luisa, Velazquez-Aviña Martha Margarita, Bolea-Murga Victoria, Torres-Nava José Refugio, Amador-Sanchez Raquel, Solis-Labastida Karina Anastacia, Rámirez-Bello Julian, Fragoso José Manuel, Mejía-Aranguré Juan Manuel

Abstract excerpt

BACKGROUND AND AIMS: Childhood acute lymphoblastic leukemia (ALL) is the leading cause of childhood cancer-related deaths worldwide. Multiples studies have shown that ALL seems to be originated by an interaction between environmental and genetic susceptibility factors. The ARID5B polymorphisms are among the most reproducible ALL associated-risk alleles in different populations. The aim of the present study was to...

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PMID: 28476190
DOI: 10.1016/j.arcmed.2016.12.003

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