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Article

Genetic abnormalities associated with acute lymphoblastic leukemia.

Cancer science - 1 Jun 2016

Yokota Takafumi, Kanakura Yuzuru

Abstract excerpt

Acute lymphoblastic leukemia (ALL) occurs with high frequency in childhood and is associated with high mortality in adults. Recent technical advances in next-generation sequencing have shed light on genetic abnormalities in hematopoietic stem/progenitor cells as the precursor to ALL pathogenesis. Based on these genetic abnormalities, ALL is now being reclassified into newly identified subtypes. Philadelphia...

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Identifiers

PMID: 26991355
DOI: 10.1111/cas.12927
PMCID: PMC4968601

Genes

IKZF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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