Article
Developmental modification of synaptic NMDAR composition and maturation of glutamatergic synapses: matching postsynaptic slots with receptor pegs.
The Biological bulletin - 1 Feb 2013
Sanders Erin M, Nguyen Michael A, Zhou Kevin C, Hanks Mary E, Yusuf Kawthar A, Cox Daniel N, Dumas Theodore C
Abstract excerpt
The numbers and types of ionotropic glutamate receptors at most vertebrate central excitatory synapses are altered as a function of changes in input activity patterns that occur during postnatal development. Activity-dependent developmental alterations in glutamate receptors underlie lasting changes in synaptic efficacy (plasticity) and metaplasticity (the plasticity of synaptic plasticity), which are critical...
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