Article
Activity-dependent site-specific changes of glutamate receptor composition in vivo.
Nature neuroscience - 1 Jun 2008
Schmid Andreas, Hallermann Stefan, Kittel Robert J, Khorramshahi Omid, Frölich Andreas M J, Quentin Christine, Rasse Tobias M, Mertel Sara, Heckmann Manfred, Sigrist Stephan J
Abstract excerpt
The subunit composition of postsynaptic non-NMDA-type glutamate receptors (GluRs) determines the function and trafficking of the receptor. Changes in GluR composition have been implicated in the homeostasis of neuronal excitability and synaptic plasticity underlying learning. Here, we imaged GluRs in vivo during the formation of new postsynaptic densities (PSDs) at Drosophila neuromuscular junctions coexpressing...
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