Article
Molecular determinants controlling NMDA receptor synaptic incorporation.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Apr 2011
Storey Granville P, Opitz-Araya Ximena, Barria Andres
Abstract excerpt
Synaptic incorporation of NMDA receptors (NMDARs) is regulated by GluN2 subunits with different rules controlling GluN2A- and GluN2B-containing receptors; whereas GluN2B-containing receptors are constitutively incorporated into synapses, GluN2A incorporation is activity-dependent. We expressed electrophysiologically tagged NMDARs in rat hippocampal slices to identify the molecular determinants controlling the...
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