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Article

Role of the functional Toll-Like receptor-9 promoter polymorphism (-1237T/C) in increased risk of end-stage renal disease: a case-control study.

PloS one - 1 Jan 2013

Yang Hsin-Yi, Lu Kuo-Cheng, Lee Herng-Sheng, Huang Shih-Ming, Lin Yuh-Feng, Wu Chia-Chao, Salter Donald M, Su Sui-Lung

Abstract excerpt

Inflammation induced by infectious and noninfectious triggers in the kidney may lead to end stage renal disease (ESRD). Toll-like receptor 9 (TLR-9) a receptor for CpG DNA is involved in activation of immune cells in renal disease and may contribute to chronic inflammatory disease progression thr...

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Identifiers

PMID: 23472199
DOI: 10.1371/journal.pone.0058444
PMCID: PMC3589433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23472199-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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