Article
Transcription factor 7-like 2 (TCF7L2) gene polymorphism and clinical phenotype in end-stage renal disease patients.
Molecular biology reports - 1 Jun 2014
Buraczynska Monika, Zukowski Pawel, Ksiazek Piotr, Kuczmaszewska Agata, Janicka Joanna, Zaluska Wojciech
Abstract excerpt
Variants of the transcription factor 7-like 2 gene (TCF7L2) have been associated with type 2 diabetes and cardiovascular disease in different populations. Here we investigated the potential association of the rs7903146 polymorphism in the TCF7L2 gene with clinical profile of end-stage renal disease (ESRD) patients. We examined a cohort of 1065 ESRD patients with diabetic and non-diabetic renal disease. The...
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