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Article

The Variations' in Genes Encoding TIM-3 and Its Ligand, Galectin-9, Influence on ccRCC Risk and Prognosis.

International journal of molecular sciences - 20 Jan 2023

Andrzejczak Anna, Tupikowski Krzysztof, Tomkiewicz Anna, Małkiewicz Bartosz, Ptaszkowski Kuba, Domin Aleksandra, Szydełko Tomasz, Karabon Lidia

Abstract excerpt

Renal cell cancer is the most common type of kidney cancer in adults, and clear cell renal cell carcinoma (ccRCC) is the most diagnosed type. T cell immunoglobulin and mucin-domain-containing-3 (TIM-3) belongs to immunological checkpoints that are key regulators of the immune response. One of the known TIM-3 ligands is galectin-9 (LGALS9). A limited number of studies have shown an association between TIM-3...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36768365
DOI: 10.3390/ijms24032042
PMCID: PMC9917084

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