Article
Genetic polymorphisms located in genes related to immune and inflammatory processes are associated with end-stage renal disease: a preliminary study.
BMC medical genetics - 20 Jul 2012
Jimenez-Sousa Ma Angeles, López Elisabeth, Fernandez-Rodríguez Amanda, Tamayo Eduardo, Fernández-Navarro Pablo, Segura-Roda Laura, Heredia María, Gómez-Herreras José I, Bustamante Jesús, García-Gómez Juan Miguel, Bermejo-Martin Jesús F, Resino Salvador
Abstract excerpt
BACKGROUND: Chronic kidney disease progression has been linked to pro-inflammatory cytokines and markers of inflammation. These markers are also elevated in end-stage renal disease (ESRD), which constitutes a serious public health problem. OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNPs) located in genes related to immune and inflammatory processes, could be associated with ESRD...
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