Article
The T-1237C polymorphism of the Toll-like receptor-9 gene is associated with chronic kidney disease in a Han Chinese population.
The Tohoku journal of experimental medicine - 1 Oct 2011
Lu Kuo-Cheng, Yang Hsin-Yi, Lin Yuh-Feng, Kao Sen-Yeong, Lai Ching-Huang, Chu Chi-Ming, Wu Chia-Chao, Su Sui-Lung
Abstract excerpt
Chronic kidney disease (CKD) is increasingly recognized as a global public health problem. As inflammatory processes and genetic factors are involved in the pathogenesis of CKD, we have investigated the potential genetic contribution of Toll-like receptor (TLR) gene polymorphisms in CKD. In a case-control association study, 149 CKD patients and 429 healthy controls were genotyped by real-time polymerase chain...
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