Article
Impact of polymorphisms of TLR4/CD14 and TLR3 on acute rejection in kidney transplantation.
Transplantation - 15 Sept 2009
Hwang Young-Hwan, Ro Han, Choi Inho, Kim Hyunsook, Oh Kook-Hwan, Hwang Jong-Ik, Park Myoung Hee, Kim Suhnggwon, Yang Jaeseok, Ahn Curie
Abstract excerpt
BACKGROUND: Organ transplantation itself inevitably activates the innate immune system by toll-like receptors (TLRs), potentially leading to allograft rejection and graft failure. We evaluated the possible association between the TLR4/CD14 and TLR3 polymorphisms of donor-recipient pairs, and acute rejection after living donor kidney transplantation. METHODS: TLR4 -1607T/C (rs10759932), -2026A/G (rs1927914); CD14...
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