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Article

Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques.

AIDS research and human retroviruses - 1 Jul 2013

Butler Katherine, Morgan Jennifer S, Hanson Debra L, Adams Debra, Garcia-Lerma J Gerardo, Heneine Walid, Ellenberger Dennis, Hendry R Michael, McNicholl Janet, Johnson Welkin E, Kersh Ellen N

Abstract excerpt

Infections following repeated, low-dose (RLD), mucal S(H)IV exposures of macaques are used to model sexual HIV exposures for biomedical prevention testing. Different susceptibilities among animals can complicate study designs. In rhesus macaques, TRIM5 alleles Q, CypA, and TFP are resistance fact...

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Identifiers

PMID: 23461569
DOI: 10.1089/aid.2012.0383
PMCID: PMC3685693

Genes

TRIM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23461569-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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