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Article

SHIV-162P3 infection of rhesus macaques given maraviroc gel vaginally does not involve resistant viruses.

PloS one - 1 Jan 2011

Tsibris Athe M N, Pal Urboshi, Schure Allison L, Veazey Ronald S, Kunstman Kevin J, Henrich Timothy J, Klasse P J, Wolinsky Steven M, Kuritzkes Daniel R, Moore John P

Abstract excerpt

Maraviroc (MVC) gels are effective at protecting rhesus macaques from vaginal SHIV transmission, but breakthrough infections can occur. To determine the effects of a vaginal MVC gel on infecting SHIV populations in a macaque model, we analyzed plasma samples from three rhesus macaques that received a MVC vaginal gel (day 0) but became infected after high-dose SHIV-162P3 vaginal challenge. Two infected macaques...

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Identifiers

PMID: 22164225
DOI: 10.1371/journal.pone.0028047
PMCID: PMC3229503

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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