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Article

ARMS-PCR for detection of BRAF V600E hotspot mutation in comparison with Real-Time PCR-based techniques.

Acta biochimica Polonica - 1 Jan 2013

Machnicki Marcin M, Glodkowska-Mrowka Eliza, Lewandowski Tomasz, Ploski Rafał, Wlodarski Pawel, Stoklosa Tomasz

Abstract excerpt

BRAF mutation testing is one of the best examples how modern genetic testing may help to effectively use targeted therapies in cancer patients. Since many different genetic techniques are employed to assess BRAF mutation status with no available comparison of their sensitivity and usefulness for different types of samples, we decided to evaluate our own PCR-based assay employing the amplification refractory...

Topics

Cell Line, Tumor
Genes, Neoplasm
Genetic Variation
Humans
Polymerase Chain Reaction
Proto-Oncogene Proteins B-raf
Real-Time Polymerase Chain Reaction

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23460942

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23460942-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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