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Article

Wobble-enhanced ARMS method for detection of KRAS and BRAF mutations.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2011

Hamfjord Julian, Stangeland Astrid M, Skrede Martina L, Tveit Kjell M, Ikdahl Tone, Kure Elin H

Abstract excerpt

Monoclonal antibodies targeting the epidermal growth factor receptor have expanded the range of treatment options for patients with metastatic colorectal cancer. However, somatic mutations in the KRAS and BRAF genes have proven to be molecular predictors of resistance to treatment with anti-epidermal growth factor receptor therapy in these patients. Thus, we have developed a sensitive mutation assay,...

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Identifiers

PMID: 21817902
DOI: 10.1097/PDM.0b013e31820b49e2

Genes

BRAF
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Wobble-enhanced ARMS method for detection of KRAS and BRAF mutations.PMID 21817902Read ↗

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