Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene.

doi:10.1590/s0074-02762013000100008

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Article

Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene.

Memorias do Instituto Oswaldo Cruz - 1 Feb 2013

Grandi Tarciana, da Silva Cláudia Maria Dornelles, Amaral Karine Medeiros, Picon Paulo Dornelles, Costi Cintia, da Fré Nicole Nascimento, Fiegenbaum Marilu, Niel Christian, Rossetti Maria Lucia Rosa

Abstract excerpt

A single-nucleotide polymorphism (SNP) upstream of interleukin (IL)28B was recently identified as an important predictor of the outcome of chronic hepatitis C patients treated with pegylated interferon plus ribavirin (PEG-IFN/RBV). The aim of this study was to investigate the association between the IL28B gene polymorphism (rs12979860) and virological response in chronic hepatitis C patients. Brazilian patients...

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Identifiers

PMID: 23440114
DOI: 10.1590/s0074-02762013000100008
PMCID: PMC3974310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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