Article
A single nucleotide polymorphism, rs129679860, in the IL28B locus is associated with the viral kinetics and a sustained virological response in a chronic, monoinfected hepatitis C virus genotype-1 Brazilian population treated with pegylated interferon-ribavirin.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2012
Ramos Juliene Antonio, Ramos Ana Lúcia de Araújo, Hoffmann Luisa, Perez Renata de Mello, Coelho Henrique Sérgio Moraes, Urményi Turán Péter, Silva Rosane, Rondinelli Edson, Villela-Nogueira Cristiane Alves
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the interleukin (IL)28B locus have been associated with a sustained virological response (SVR) in interferon-ribavirin (IFN-RBV)-treated chronic hepatitis C virus (HCV)-infected patients in European and African populations. In this study, the genotype frequency of two IL28B SNPs (rs129679860 and rs8099917) in a cohort of chronic HCV-monoinfected patients in Brazil was...
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