Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A genetic variant in the interleukin 28B gene as a major predictor for sustained virologic response in chronic hepatitis C virus infection.

Archives of medical research - 1 Aug 2015

Sixtos-Alonso Ma Sara, Avalos-Martinez Rosalba, Sandoval-Salas Ricardo, Dehesa-Violante Margarita, García-Juarez Ignacio, Chávez-Ayala Alejandro, Domínguez-López Aarón, Vargas-Vorácková Florencia, Toapanta-Yanchapaxi Liz, Amezcua-Guerra Luis Manuel, Uribe Misael, Sánchez-Ávila Juan Francisco

Abstract excerpt

BACKGROUND AND AIMS: The IL28B single nucleotide polymorphism (SNP) rs12979860 is a major predictor of treatment outcomes in hepatitis C virus (HCV) infection, but its distribution widely varies among populations and ethnicities. We undertook this study to investigate the distribution of IL28B SNP rs12979860 in Mexican patients with HCV infection and to assess its usefulness in predicting response to pegylated...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antiviral Agents
Share to Cohort Studies
Share to Genetic Variation
Share to Hepatitis C, Chronic
Share to Interferons
Share to Interleukins
Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 26189761
DOI: 10.1016/j.arcmed.2015.07.001

Genes

NNT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic variant in the interleukin 28B gene as a major predictor for sustained virologic response in chronic hepatitis C virus infection.PMID 26189761Read ↗

IL28B polymorphisms predict the response to chronic hepatitis C virus infection treatment in a Mexican population.Semantic proximity Read ↗

Relationship between the genetic variation in interleukin 28B and response to antiviral therapy in patients with chronic hepatitis C.Semantic proximity Read ↗

Assessment of IL-28: rs12979860 and rs8099917 Polymorphisms in a Cohort of Cuban Chronic HCV Genotype 1b Patients.Semantic proximity Read ↗

Replicated association between an IL28B gene variant and a sustained response to pegylated interferon and ribavirin.Semantic proximity Read ↗

Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study.Semantic proximity Read ↗

Predicting response to therapy in chronic hepatitis C: an approach combining interleukin-28B gene polymorphisms and clinical data.Semantic proximity Read ↗

IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection.Semantic proximity Read ↗

Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes.Semantic proximity Read ↗

Prediction of response to pegylated interferon plus ribavirin by IL28B gene variation in patients coinfected with HIV and hepatitis C virus.Semantic proximity Read ↗

Role of interleukin 28B-related gene polymorphisms in chronic hepatitis C and the response to antiviral therapy in Koreans.Semantic proximity Read ↗

Meta-analysis: IL28B polymorphisms predict sustained viral response in HCV patients treated with pegylated interferon-α and ribavirin.Semantic proximity Read ↗

A single nucleotide polymorphism, rs129679860, in the IL28B locus is associated with the viral kinetics and a sustained virological response in a chronic, monoinfected hepatitis C virus genotype-1 Brazilian population treated with pegylated interferon-ribavirin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.