Article
Relationship between the genetic variation in interleukin 28B and response to antiviral therapy in patients with chronic hepatitis C.
Chinese medical journal - 1 Jul 2012
Xie Jun-Qiang, Guo Xiao-Yan, Zhang Xiao-Hong, Lin Bing-Liang, Xie Dong-Ying, Gao Zhi-Liang, Wang Gen-Shu, Zhao Zhi-Xin
Abstract excerpt
BACKGROUND: Genetic variations at the interleukin 28B (IL-28B) locus are important in predicting outcome following therapy for chronic hepatitis C virus (HCV) infection. The aim of this research was to evaluate the role of IL-28B single nucleotide polymorphism (SNP) variations in Chinese patients undergoing pegylated interferon-α plus ribavirin (PEG-IFN-α/RBV) treatment. METHODS: To determine the effect of IL-28B...
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