Article
Polymorphism near the IL28B gene in Korean hepatitis C virus-infected patients treated with peg-interferon plus ribavirin.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Dec 2011
Lyoo Kwangsoo, Song Myeong Jun, Hur Wonhee, Choi Jung Eun, Hong Sung Woo, Kim Chang Wook, Bae Si Hyun, Choi Jong Young, Choi Sang Wook, Shin Eui-Cheol, Yoon Seung Kew
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) near the IL28B gene have recently been described as predictors of antiviral therapy responses in patients with hepatitis C virus (HCV) genotype-1. OBJECTIVES: The aim of this study was to investigate the association between genetic variation near the IL28B gene and treatment outcome prediction in Korean patients receiving peg-interferon (PEG-IFN) plus ribavirin...
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