Article
Genetic variation in interleukin-28B predicts SVR in hepatitis C genotype 1 Argentine patients treated with PEG IFN and ribavirin.
Annals of hepatology - 1 Jan 2000
Ridruejo Ezequiel, Solano Angela, Marciano Sebastián, Galdame Omar, Adrover Raúl, Cocozzella Daniel, Delettieres Dreanina, Martínez Alfredo, Gadano Adrián, Mandó Oscar G, Silva Marcelo O
Abstract excerpt
BACKGROUND AND AIMS: Genetic variations in the interleukin 28B (IL28B) gene have been associated with viral response to PEG-interferon-α/ribavirin (PR) therapy in hepatitis C virus (HCV) genotype 1 infected patients from North America, Europe and Asia. The importance of these IL28B variants for Argentine patients remains unknown. MATERIAL AND METHODS: IL28B host genotypes (rs8099917 and rs12979860) were...
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