Article
Interleukin 28B-related polymorphisms: a pathway for understanding hepatitis C virus infection?
World journal of gastroenterology - 14 Nov 2013
Garcia Raquel Francine Liermann, Moreira Simone, de Araújo Ramos Ana Lucia, Ferreira Leslie Ecker, de Mattos Angelo Alves, Tovo Cristiane Valle, Nader Lysandro Alsina, Ramos Juliene Antonio, Rondinelli Edson, de Jesus Dominici Arnaldo, Garcia Christian Evangelista, de Souza Leite Pinho Mauro, Brandão-Mello Carlos Eduardo, Villela-Nogueira Cristiane Alves, de França Paulo Henrique Condeixa
Abstract excerpt
AIM: To analyze the role of rs12979860 and rs8099917 polymorphisms in hepatitis C virus (HCV) genotype 1 infection of Brazilians. METHODS: A total of 145 adult patients diagnosed with genotype 1 chronic hepatitis C (CHC) who had completed a 48-wk regimen of pegylated-interferon α-2a or -2b plus ribavirin combination therapy were recruited from six large urban healthcare centers and 199 healthy blood donors...
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