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Article

Meta-analyses on the association of MTR A2756G and MTRR A66G polymorphisms with neural tube defect risks in Caucasian children.

The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Aug 2013

Ouyang Shengrong, Liu Zhuo, Li Yuanyuan, Wu Jianxin

Abstract excerpt

OBJECTIVE: Methionine synthase (MTR) and MTR reductase (MTRR) genes have been considered to be implicated in the development of neural tube defects (NTDs). The associations between MTR A2756G and MTRR A66G polymorphisms and NTD risk in children have been investigated in many studies. However, results are inconsistent. Accordingly, we conducted meta-analyses to further investigate such associations. METHODS:...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23425389
DOI: 10.3109/14767058.2013.777699

Genes

MTR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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