Article
Association between MTR A2756G and MTRR A66G polymorphisms and maternal risk for neural tube defects: a meta-analysis.
Gene - 25 Feb 2013
Ouyang Shengrong, Li Yuanyuan, Liu Zhuo, Chang Huibo, Wu Jianxin
Abstract excerpt
BACKGROUND: Methionine synthase (MTR) and methionine synthase reductase (MTRR) genes have been considered to be implicated in the development of neural tube defects (NTDs). However, the results are inconsistent. Accordingly, we conducted a meta-analysis to further investigate such an association. METHODS: Published literature from PubMed and Embase databases was retrieved. All studies evaluating the association...
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