Article
Mapping genetic variants in the CFH gene for association with leprosy in Han Chinese.
Genes and immunity - 1 Oct 2014
Zhang D-F, Wang D, Li Y-Y, Yao Y-G
Abstract excerpt
Complement factor H (CFH) is an essential regulator in the homeostasis of the complement system that plays multiple roles in leprosy. We previously reported a preliminary association of CFH with leprosy, but potentially causal variants remain to be identified. In this study, we performed a fine-mapping association analysis in 1110 individuals (527 leprosy patients and 583 controls) followed by bioinformatic...
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