Article
Genetic variants of the MRC1 gene and the IFNG gene are associated with leprosy in Han Chinese from Southwest China.
Human genetics - 1 Jul 2012
Wang Dong, Feng Jia-Qi, Li Yu-Ye, Zhang Deng-Feng, Li Xiao-An, Li Qing-Wei, Yao Yong-Gang
Abstract excerpt
Leprosy is an ancient infectious disease, with over 200,000 affected people (mainly in Asia and Africa) being registered annually. Genetic factors may confer susceptibility to this disease. In the present study, we genotyped 12 genetic variants of the MRC1 gene and the IFNG gene in 527 Han Chinese with leprosy and 583 healthy individuals from Yunnan, China, to discern potential association of these two genes with...
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