Article
Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Sept 2013
García-Ibarbia C, Pérez-Núñez M I, Olmos J M, Valero C, Pérez-Aguilar M D, Hernández J L, Zarrabeitia M T, González-Macías J, Riancho J A
Abstract excerpt
UNLABELLED: Two missense polymorphisms of WNT16 were associated with hip bone mineral density (BMD), the buckling ratio of the femoral neck, calcaneal ultrasound and hip fractures in individuals under 80 years of age. These results confirm the association of the WNT16 gene with bone mass and osteoporotic fractures. INTRODUCTION: Osteoporosis has a strong genetic component. Wnt ligands stimulate the...
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