Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Heritable Recombination system for synthetic Darwinian evolution in yeast.

ACS synthetic biology - 21 Dec 2012

Romanini Dante W, Peralta-Yahya Pamela, Mondol Vanessa, Cornish Virginia W

Abstract excerpt

Genetic recombination is central to the generation of molecular diversity and enhancement of evolutionary fitness in living systems. Methods such as DNA shuffling that recapitulate this diversity mechanism in vitro are powerful tools for engineering biomolecules with useful new functions by directed evolution. Synthetic biology now brings demand for analogous technologies that enable the controlled recombination...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Biomarkers
Share to DNA Shuffling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis

Share to Plasmids

Share to Recombination, Genetic

Share to Reproduction

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 23412545
DOI: 10.1021/sb3000904
PMCID: PMC3569010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Heritable Recombination system for synthetic Darwinian evolution in yeast.PMID 23412545Read ↗

In vivo site-directed recombination (SDR): An efficient tool to reveal beneficial epistasis.Semantic proximity Read ↗

A synthetic RNA-mediated evolution system in yeast.Semantic proximity Read ↗

The evolving art of creating genetic diversity: From directed evolution to synthetic biology.Semantic proximity Read ↗

A synthetic RNA-mediated evolution system in yeastSemantic proximity Read ↗

Generating combinatorial diversity via engineered V(D)J-like recombination in Saccharomyces cerevisiaeSemantic proximity Read ↗

Rapid, scalable, combinatorial genome engineering by Marker-less Enrichment and Recombination of Genetically Engineered loci (MERGE)Semantic proximity Read ↗

SCRaMbLE-in: A Fast and Efficient Method to Diversify and Improve the Yields of Heterologous Pathways in Synthetic Yeast.Semantic proximity Read ↗

Heterozygous diploid and interspecies SCRaMbLEing.Semantic proximity Read ↗

SCRaMbLE: a Versatile Tool for Genome Manipulation.Semantic proximity Read ↗

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening.Semantic proximity Read ↗

Genome shuffling leads to rapid phenotypic improvement in bacteria.Semantic proximity Read ↗

A recombinatorial method useful for cloning dominant alleles in Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.