Article
The evolving art of creating genetic diversity: From directed evolution to synthetic biology.
Biotechnology advances - 1 Jan 2000
Currin Andrew, Parker Steven, Robinson Christopher J, Takano Eriko, Scrutton Nigel S, Breitling Rainer
Abstract excerpt
The ability to engineer biological systems, whether to introduce novel functionality or improved performance, is a cornerstone of biotechnology and synthetic biology. Typically, this requires the generation of genetic diversity to explore variations in phenotype, a process that can be performed at many levels, from single molecule targets (i.e., in directed evolution of enzymes) to whole organisms (e.g., in...
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