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SCRaMbLE: a Versatile Tool for Genome Manipulation.

Physiology (Bethesda, Md.) - 1 Sept 2025

Cheng Li, Li Jielin, Chen Yaojun, Dai Junbiao

Abstract excerpt

Genomic rearrangements play an important role in shaping genetic diversity, as they enable the generation of novel structural variations through specific genome manipulation tools. These variations contribute to phenotypic differences among individuals within a population, thereby serving as the foundation for natural selection and driving evolutionary processes. In recent years, synthetic chromosome...

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PMID: 39938087
DOI: 10.1152/physiol.00049.2024

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