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Article

The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De)differentiation.

Cell reports - 21 Feb 2013

Haenebalcke Lieven, Goossens Steven, Dierickx Pieterjan, Bartunkova Sonia, D'Hont Jinke, Haigh Katharina, Hochepied Tino, Wirth Dagmar, Nagy Andras, Haigh Jody J

Abstract excerpt

Control of cellular (de)differentiation in a temporal, cell-specific, and exchangeable manner is of paramount importance in the field of reprogramming. Here, we have generated and characterized a mouse strain that allows iPSC generation through the Cre/loxP conditional and doxycycline/rtTA-controlled inducible expression of the OSKM reprogramming factors entirely from within the ROSA26 locus. After reprogramming,...

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Identifiers

PMID: 23395636
DOI: 10.1016/j.celrep.2013.01.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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