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Article

The [PSI+] prion exists as a dynamic cloud of variants.

PLoS genetics - 1 Jan 2013

Bateman David A, Wickner Reed B

Abstract excerpt

[PSI(+)] is an amyloid-based prion of Sup35p, a subunit of the translation termination factor. Prion "strains" or "variants" are amyloids with different conformations of a single protein sequence, conferring different phenotypes, but each relatively faithfully propagated. Wild Saccharomyces cerevisiae isolates have SUP35 alleles that fall into three groups, called reference, Δ19, and E9, with limited...

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Share to Amino Acid Sequence
Share to Amyloidogenic Proteins
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Termination Factors

Share to Polymorphism, Genetic

Share to Prions

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

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Identifiers

PMID: 23382698
DOI: 10.1371/journal.pgen.1003257
PMCID: PMC3561065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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