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Article

Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion.

The EMBO journal - 15 Nov 2001

Uptain S M, Sawicki G J, Caughey B, Lindquist S

Abstract excerpt

Yeast prions are protein-based genetic elements that produce phenotypes through self-perpetuating changes in protein conformation. For the prion [PSI(+)] this protein is Sup35, which is comprised of a prion-determining region (NM) fused to a translational termination region. [PSI(+)] strains (variants) with different heritable translational termination defects (weak or strong) can exist in the same genetic...

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Identifiers

PMID: 11707395
DOI: 10.1093/emboj/20.22.6236
PMCID: PMC125732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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