Article
W8, a new Sup35 prion strain, transmits distinctive information with a conserved assembly scheme.
Prion - 1 Jan 2015
Huang Yu-Wen, Chang Yuan-Chih, Diaz-Avalos Ruben, King Chih-Yen
Abstract excerpt
Prion strains are different self-propagating conformers of the same infectious protein. Three strains of the [PSI] prion, infectious forms of the yeast Sup35 protein, have been previously characterized in our laboratory. Here we report the discovery of a new [PSI] strain, named W8. We demonstrate its robust cellular propagation as well as the protein-only transmission. To reveal strain-specific sequence...
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