Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inter-allelic prion propagation reveals conformational relationships among a multitude of [PSI] strains.

PLoS genetics - 1 Sept 2011

Lin Jia-Yu, Liao Tzu-Ya, Lee Han-Chung, King Chih-Yen

Abstract excerpt

Immense diversity of prion strains is observed, but its underlying mechanism is less clear. Three [PSI] prion strains--named VH, VK, and VL--were previously isolated in the wild-type yeast genetic background. Here we report the generation and characterization of eight new [PSI] isolates, obtained by propagating the wild-type strains with Sup35 proteins containing single amino-acid alterations. The VH strain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid
Share to Haploidy
Share to Homozygote

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Termination Factors

Share to Prions

Share to Recombinant Proteins

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21980301
DOI: 10.1371/journal.pgen.1002297
PMCID: PMC3183073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inter-allelic prion propagation reveals conformational relationships among a multitude of [PSI] strains.PMID 21980301Read ↗

Supporting the structural basis of prion strains: induction and identification of [PSI] variants.Semantic proximity Read ↗

W8, a new Sup35 prion strain, transmits distinctive information with a conserved assembly scheme.Semantic proximity Read ↗

The [PSI+] prion exists as a dynamic cloud of variants.Semantic proximity Read ↗

Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+].Semantic proximity Read ↗

The Sup35 domains required for maintenance of weak, strong or undifferentiated yeast [PSI+] prions.Semantic proximity Read ↗

Structural insights into a yeast prion illuminate nucleation and strain diversity.Semantic proximity Read ↗

[Psi(+)] prion generation in yeast: characterization of the 'strain' difference.Semantic proximity Read ↗

Conformation preserved in a weak-to-strong or strong-to-weak [PSI+] conversion during transmission to Sup35 prion variants.Semantic proximity Read ↗

Effect of domestication on the spread of the [PIN+] prion in Saccharomyces cerevisiae.Semantic proximity Read ↗

Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion.Semantic proximity Read ↗

Effect of charged residues in the N-domain of Sup35 protein on prion [PSI+] stability and propagation.Semantic proximity Read ↗

The role of the N-terminal oligopeptide repeats of the yeast Sup35 prion protein in propagation and transmission of prion variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.