Article
The [PSI+] prion of yeast: a problem of inheritance.
Methods (San Diego, Calif.) - 1 May 2006
Tuite Mick F, Cox Brian S
Abstract excerpt
The [PSI(+)] prion of the yeast Saccharomyces cerevisiae was first identified by Brian Cox some 40 years ago as a non-Mendelian genetic element that modulated the efficiency of nonsense suppression. Following the suggestion by Reed Wickner in 1994 that such elements might be accounted for by invoking a prion-based model, it was subsequently established that the [PSI(+)] determinant was the prion form of the...
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