Article

Identification and functional characterisation of gene fusions in human cancer cell lines

2018-01-01

Abstract excerpt

Advances in next-generation sequencing have accelerated the rate at which novel gene fusions are discovered. The discovery of gene fusions such as EML4-ALK in lung cancer and BCR-ABL1 in chronic myeloid leukaemia have already led to changes in clinical care. However, important questions remain about the role of gene fusions in promoting oncogenic phenotypes and their relevance in drug response. In this study, I co...

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Literature Corpus work: 16585d5c-5157-50c0-b37c-fa03e848d0fe
DOI: 10.17863/cam.40285

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